Sasako et al. show that disruption of the insulin/IGF-1 signaling by suppressing Akt activity in mouse skeletal muscle can accelerate osteosarcopenia and shortens lifespan, which is reversed by inactivation of FoxOs rather than activation of mTOR, suggesting FoxOs as therapeutic targets.
The Onion’s brief takes a satirical approach to convince the Supreme Court to take up a case involving free speech and qualified immunity.
Even with the growing energy crisis, nuclear capacity is declining in the U.S. and Europe, while China, India, and South Korea have plans for nuclear expansion.
VAL-D’OR, Québec, Oct. 05, 2022 (GLOBE NEWSWIRE) -- Pershimex Resources Corporation (« Pershimex » or « the Company») (TSX Venture: PRO) is pleased...
More employers are sharing how much jobs pay. Could increased transparency help close the pay gap for women and people of color?
Illinois Law dean Vikram David Amar and professor Jason Mazzone comment on recent comments by U.S. Supreme Court Justice Elena Kagan expressing reservations about doctrinal changes attributable to the...
The Cowboys defense is off to a hot start through four games in their role as the team’s “thermostat,” as head coach Mike McCarthy says.
It is indeed to be regretted that an economic historian such as the new Chancellor should appear to be so cavalier in his attitude to financial markets, given his reliance on them to fund his borrowing and attract inward investment into sterling.
On the heels of the Pittsburgh Steelers losing on Sunday to the New York Jets at home, it certainly feels like rookie quarterback Kenny Pickett will be named the team’s new starter by head coach Mike Tomlin this week. If indeed that’s the case, what will happen to former starter Mitch Trubisky? Coul…
The likes of Italy’s Meloni have portrayed themselves as defenders of Arab Christians, only to embrace their tormentors.
“All regions will be affected, but alarm bells are ringing most for developing countries, many of which are edging closer to debt default,” the UNCTAD warned.
Emmanuel Macron is quick to talk of a tough stance against Russia, but the truth is that France’s supports for Ukraine falls well short.
On October 1, yet another military coup took place in Burkina Faso, just nine months after the country’s previous military coup in January 2022, signaling deteriorating security and stability in the Sahel. In response, France advised against all travel to Burkina Faso not only because of the increas…
Is there any relief for Americans as interest rates climb and inflation remains high?
Emmanuel Amuneke: Mission to Zambia THISDAY Newspapers
Globally, the A330-800 is a rare aircraft. But now, Kuwait Airways has four of the six examples in active commercial service.
ESG—environmental, social, and governance—has been the new hot topic for the last several years. Yet companies are still trying to come to grips with...
Cryptocurrencies spur financial inclusion, protect against inflation and enhance the global economy despite the recession.
In the game of football, if you are not united together as a cohesive team, you don’t stand a chance against the opposition or outside forces looking to pull you apart. The Steelers are going through some trials to start the 2022 season, as the offense has been heavily criticized for their poor perf…
Leeds United face a tough task in convincing Jack Harrison to remain at the club amid interest from other sides, as per one journalist.