I am looking to get a rental and hitch a U haul trailer for a road trip. Do the rentals have tow hooks

Most do not, and if they happen to they almost always explicitly state that towing is not allowed and wouldn't be covered in the event of an accident.

Just use a U-Haul truck as your rental.

My wife doesn’t want to drive the U haul since it’s a long drive excess of 15 hrs so we were looking for a car/ truck. Will have to call the enterprise hertz folk to enquirer

Not sure. How about a shipping a container & cars, then y’all fly? That worked well for us. You can also drive the uhaul and let your wife fly.

Nope. Not going to find one with a hitch. If it's a round trip you can rent a U-Haul pickup. Otherwise, rent a 10' truck and fill that up instead.