Web dev Python tech stack -> JS

Applying to new jobs in web development. I currently have experience within Python tech stacks (Flask, Postgres, Vue) and saw many job postings require experience with the JS trifecta (Typescript, GraphQL, React). Should I take the leap and apply? Or get some side projects under my belt with the stack before doing so? I prefer learning on the job so if companies would take me now I wouldn’t object to only focusing on leetcode. YOE: 2 TC: 120k Boston