Do any major apps use react native, or are all of the top apps using Java or obj C / swift? Can apps run 100% as smooth as the native programming language, or is it always 5-10% worse frame rate when scrolling and doing processor intensive activities?
Obviously Facebook and Instagram. Airbnb too
Only very small parts of the flagship Facebook and Instagram apps use react native https://engineering.instagram.com/react-native-at-instagram-dd828a9a90c7
Ok, so it sounds like you need a very thoughtful and competent team who will measure things. Secondly, it appears they were porting things that were originally implemented as WebViews, to ship faster. So... what I'm getting out of this is, why ReactNative instead of just native?
TIL about multi-DEX: https://developer.android.com/studio/build/multidex.html#about
Reasons to use React Native instead of pure native would be: code sharing across platforms, ability to release updates without going through google play or Apple approvals, faster edit-compile-test loop. For larger companies it's more feasible to fund 2 dev teams but smaller places that may not be possible.
GoDaddy is very heavy on react native - we have one mini app: flare in the app store that is RN and we are working on a huge app that will be RN too.
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If you want native, write Java or Swift/ObjC